Rep. Shelley Moore Capito (R-W.Va.) was the first blue-state Senate pickup for the Republican Party tonight.
She also becomes the first woman to represent West Virginia in the upper chamber.
Capito held a steady lead over her Democratic opponent, Secretary of State Natalie Tennant, to replace retiring Sen. Jay Rockefeller (D-W.Va.).
Capito was leading 60 percent to 38 percent for Tennant with about one percent of precincts reporting.
Tennant brought in liberal Sen. Elizabeth Warren (D-Mass.) to campaign on her behalf, a curious choice for a candidate campaigning as a centrist in a coal state.