June 24, 2020

I’VE SPECULATED BEFORE THAT THE INNATE IMMUNE SYSTEM MAY BE MORE IMPORTANT THAN ANTIBODIES. NOW THERE’S THIS: Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune Response without Seroconversion. “Exposure to SARS-CoV-2 can induce virus-specific T cell responses without seroconversion. T cell responses may be more sensitive indicators of SARS-Co-V-2 exposure than antibodies. Our results indicate that epidemiological data relying only on the detection of SARS-CoV-2 antibodies may lead to a substantial underestimation of prior exposure to the virus.”

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