FASTER, PLEASE: ‘Unheard of’ responses to bluebird CAR-T therapy seen in myeloma study.. “More than half of patients with advanced multiple myeloma who had run out of therapeutic options remained in complete remission after receiving bluebird bio Inc’s experimental gene-modifying immunotherapy in a small, early stage study, according to updated data released on Sunday. Of 18 patients who received a therapeutic dose of bb2121, all but one responded to the treatment, a 94 percent response rate, while 56 percent remained in remission with a median follow-up of 40 weeks after treatment. . . . bb2121 belongs to a potentially revolutionary new type of one-time treatment called CAR-T therapy that involves genetic manipulation of a patient’s immune system. A patient’s own disease-fighting T-cells are harvested and genetically reengineered to target specific proteins on cancer cells before being replaced so they can circulate seeking out and attacking the cancer, possibly for years.”