PROGRESS? Female Athletes Are Closing The Gender Gap When It Comes To Concussions.

“We classically have always known the male response to brain injury,” says Mark Burns, at Georgetown University. But there have been remarkably few studies of females. The bias runs throughout the scientific literature, even in studies of mice.

“Male mice have been used historically in research and not really been compared to female mice,” he says.

That’s changing now. The National Institutes of Health recently began to require scientists to include female animals.

Burns’ lab has begun using both sexes in research on head injuries. And they’re finding some differences. This summer, Burns published a study in the journal Glia that looked at mice with severe brain injuries. He says the brains of male mice showed a massive immune response within a day, but the female response was much slower — up to seven days.

Given traditional roles, unlike men there was probably little evolutionary advantage for women to rapidly heal from concussions.