EUDAIMONIA, HEDONISM, AND GENES:

When they parsed the data, they saw that Fredrickson’s prediction appeared to be wrong. “This whole hedonic well-being stuff—just how happy are you, how satisfied with life?—didn’t really correlate with gene expression at all,” Cole said. Then he checked the correlation with eudaemonic happiness. “When we looked at that, things actually looked quite impressive,” he said. The results, while small, were clearly significant. “I was rather startled.” The study indicated that people high in eudaemonic happiness were more likely to show the opposite gene profile of those suffering from social isolation: inflammation was down, while antiviral response was up. Since that first test, in 2013, there have been three successful replications of the study, including one of a hundred and eight people, and another of a hundred and twenty-two. According to Cole, the kind of effect sizes that are being found indicate that lacking eudaemonia can be as damaging as smoking or obesity. They also suggest that, although people high in eudaemonic happiness often experience plenty of the hedonic stuff, too, the associated health benefits tend to surface only in those who lead what Aristotle might have called a good life.

Unrelated: Would a New Yorker writer use a phrase like “polluted by Christian moralizing” about any other religion?