THE HOLY GRAIL OF STEM-CELL SCIENCE?

Only a few days ago an article in the leading journal Nature brought amazing news. A Japanese team at Kyoto University has discovered how to reprogram skin cells so that they “dedifferentiate” into the equivalent of an embryonic stem cell. From this they can be morphed, theoretically, into any cell in the body, a property called pluripotency. It could be the Holy Grail of stem cell science: a technique that is both feasible and unambiguously ethical. . . .

This is mainstream research, not an eccentric theory from a Romanian naturopathy journal. Yamanaka’s work has been confirmed by two other teams affiliated with the Massachusetts Institute of Technology, Harvard University and the University of California, Los Angeles — both of them headed by ardent supporters of embryonic stem cell research.

They say that the reprogrammed cells meet all the tests of pluripotent cells — they form colonies, propagate continuously and form cancerous growths called teratomas, as well as producing chimaeras. “Its unbelievable, just amazing,” says Hans Schöler, a German stem cell expert. “For me, it’s like Dolly. It’s that type of an accomplishment.”

I have no qualms about embryonic stem cell research, but this is obviously a big deal if it pans out.