THIS EXPLAINS SHELDON COOPER’S SISTER: Prenatal testosterone linked to long-term effects in females who share womb with male twin. “Women who shared their mother’s womb with a male twin are less likely to graduate from high school or college, have earned less by their early 30s, and have lower fertility and marriage rates when compared with twins who are both female, according to new Northwestern University research. One explanation for the long-term effects the researchers discovered is changes in behavior, which have previously been demonstrated in girls with male twins.”

So there is such a thing as “testosterone poisoning” after all, it just occurs in women.