I think that’s probably what the concept of nuking them would entail: decapitation. From what I’ve read, their nuclear facilities are spread around and are in public areas and/or deeply underground, so bombing a facility like the one in Syria and getting it right the first time would be problematic.

If I were planning, I’d go for surgical strikes for the nuclear facilities that are gettable-to, even if they are in the middle of a city, and I’d also be aiming for Ahmadinnerjacket and the first tier or three of mullah’s. Then I’d use the burrowing down bunker-buster bombs as a back-up, hoping to get lucky on the remaining nuclear facilities buried underground.

Note that technically, these probably wouldn’t be nuclear bombs as we understand them from Hiroshima, but would be newer-developed with more precise aims that I’m thinking aren’t necessarily radioactive.