NANOTECHNOLOGY UPDATE: DNA nanomachines more stable than expected in human serum and blood.
NANOTECHNOLOGY UPDATE: Bloodstream Nanobots. “Scientists are reporting in the ACS journal Nano Letters the development of new nanobots that can move easily through body fluids to their targets.”
NANOTECHNOLOGY UPDATE: Conference Video: Bionanotechnology.
NANOTECHNOLOGY UPDATE: Computational nanotechnology reveals complex interactions in double-walled carbon nanotubes.
NANOTECHNOLOGY UPDATE: Arrays of pure semiconducting carbon nanotubes for nanoelectronics.
NANOTECHNOLOGY UPDATE: Preserving protein function in DNA-protein nanostructures.
NANOTECHNOLOGY UPDATE: Single molecule pump concentrates small molecules.
NANOTECHNOLOGY UPDATE: Conference video: Multi-Million Atom Simulations for Single Atom Transistor Structures.
NANOTECHNOLOGY UPDATE: How Nanomaterials Can Help Make Fuel from Sunlight.
NANOTECHNOLOGY UPDATE: UK SuperSTEM facility advances imaging and analysis of materials.
NANOTECHNOLOGY UPDATE: Nanoparticles shepherd DNA into cells to regulate immune response.
NANOTECHNOLOGY UPDATE: Nanothreads Formed From Smallest Possible Diamonds.
NANOTECHNOLOGY UPDATE: Science and technology roadmaps for nanotechnology.
NANOTECHNOLOGY UPDATE: Gold nanotubes engineered for diagnosis and therapy.
NANOTECHNOLOGY UPDATE: Flexible supercapacitor from stacked nanomaterial.
NANOTECHNOLOGY UPDATE: Solid-phase synthesis of custom-made DNA nanotubes.
NANOTECHNOLOGY UPDATE: New scaffold for nanotechnology engineered from amyloid-like proteins.
NANOTECHNOLOGY UPDATE: Cotranscriptional folding of single RNA strand added to nanotechnology toolkit. “Since genetic information and the catalysis of chemical reactions are the two most basic functions of the molecular machinery of life, it is of considerable interest to explore what role RNA nanotechnology could play in developing the artificial molecular machine systems that will lead both to near term advances in various areas of nanotechnology and to the ultimate development of high-throughput atomically precise manufacturing (APM). Structural DNA nanotechnology predates RNA nanotechnology by a decade or more, and one of the key developments in building more complex nanostructures and devices from DNA has been DNA origami. So, what might we expect from last summer’s introduction of RNA origami?”
NANOTECHNOLOGY UPDATE: Automated synthesis expands nanotechnology building block repertoire. “The main limitation right now is that only 200 building blocks are available that carry both the halogen and the boronate groups, so only these can be used anywhere other than the first or last building block in the chain. If several thousand new building blocks become commercially available, it may not be too much of an exaggeration to talk about 3D printing of small molecules. . . . t will no doubt take several years to see just how big, how diverse, and how complex the products of this molecule synthesizer can be. It seems reasonable to expect a huge effect on drug discovery and other practical areas. Will it contribute to the development of APM? For example, could it synthesize small diamondoid parts? Could it produce useful catalysts or other functional components to attach to a large structural DNA framework? Or perhaps components for smaller, stiffer structural frameworks?” Faster, please.
Microscopic drones which can seek outand repair sections of artery damage could signal the future of treatments for heart disease and strokes, scientists claim.
Successful tests of the nanodrones have been carried out in mice – and researchers hope to conduct the first human trials soon.
The tiny particles are 1,000 times smaller than the tip of a human hair, and are designed to latch on to atherosclerotic plaques – hard deposits made from accumulated fat, cholesterol and calcium that build up on the walls of arteries and are prone to rupture, producing dangerous clots.
Once they have attached, they release a drug derived from a natural protein which can repair damage in the body.
In the mice, scientists found that just five weeks of treatment resulted in significant repairs to artery damage while the plaques were shrunk and stabilised, making it less likely for fragments to break off and cause clots.
Fritz Fiedler and I wrote about something similar 20 years ago in our Legal Problems of Nanotechnology: An Overview, which was the first nanotechnology-related law review article ever published.
NANOTECHNOLOGY UPDATE: What Will The Future Of Molecular Manufacturing Really Be Like? This really describes early-mature nanotechnology, though, not fully-developed molecular manufacturing.
NANOTECHNOLOGY UPDATE: Designing mechanical functions into DNA nanotechnology.
NANOTECHNOLOGY UPDATE: Nanotechnology making 3D transistors by directed molecular self-assembly.
NANOTECHNOLOGY UPDATE: Simple nanotechnology modification of alumina surface discourages bacteria.
NANOTECHNOLOGY UPDATE: Mixing two types of nanoparticle triggers structure change.
NANOTECHNOLOGY UPDATE: Adding layer to a piezoelectric nanostructure increases output voltage.
NANOTECHNOLOGY UPDATE: Penta-graphene a new form of carbon for chemistry and nanotechnology.
NANOTECHNOLOGY UPDATE: A tunable hinge joint for DNA nanotechnology.
NANOTECHNOLOGY UPDATE: Structural DNA nanotechnology with programmed motions.
FASTER, PLEASE: Nanotechnology May Provide More Effective Cancer Treatment.
FASTER, PLEASE: Nanotechnology And Radical Abundance.
NANOTECHNOLOGY UPDATE: Computational framework for structural DNA nanotechnology.
NANOTECHNOLOGY UPDATE: Swarms of DNA nanorobots execute complex tasks in living animal.
NANOTECHNOLOGY UPDATE: Small molecule nanorobot walks through a protein nanopore.
NANOTECHNOLOGY UPDATE: New software reveals more molecular machine structures.
NANOTECHNOLOGY UPDATE: Large, open protein cages designed and built.
NANOTECHNOLOGY UPDATE: Broadening the synthetic biology path to molecular nanotechnology.
NANOTECHNOLOGY UPDATE: Large, Open Protein Cages Designed And Built.
NANOTECHNOLOGY UPDATE: How Nanobot Swarms Will Hunt Down Cancer Cells. Faster, please.
NANOTECHNOLOGY UPDATE: Nearly perfect carbon nanotubes key to energy-saving lights.
NANOTECHNOLOGY UPDATE: Micrometer-scale structures built from DNA bricks.
I AM, AS MOST READERS KNOW, GENERALLY A TECHNO-OPTIMIST. But mocking Elon Musk for his fears about Artificial Intelligence is silly.
The article might have interviewed James Miller for more on what Musk is talking about. Here’s my interview with Miller. Says Miller about strong AIs: “I think the default path is that they treat us horribly.” Also, “gray goo” isn’t a AI-gone-bad scenario, it’s a nanotechnology-gone-bad scenario, and a somewhat exaggerated one.
NANOTECHNOLOGY UPDATE: Using DNA nanotechnology to cast arbitrarily shaped nanoparticles.
NANOTECHNOLOGY UPDATE: New Nanomaterial Scrubs Submarine Air.
NANOTECHNOLOGY UPDATE: NSF Grant program to support nanotechnology and other infrastructure.
NANOTECHNOLOGY UPDATE: DNA nanotechnology and the atoms-to-micrometer nanofabrication gap.
NANOTECHNOLOGY UPDATE: A Breakthrough In 3D Imaging By EM Alone.
NANOTECHNOLOGY UPDATE: Tailoring the shapes of organic molecules by assembly-line synthesis.
NANOTECHNOLOGY UPDATE: DNA nanotechnology and the atoms to micrometer nanofabrication gap.
NANOTECHNOLOGY UPDATE: Novel multifunctional nanoparticle for diagnosis and therapy. “A variety of nanoparticles have been designed for multiple nanomedical purposes. An article at KurzweilAI.net presents news from UC Davis of a ‘nanoporphyrin’ platform for developing multifunctional nanoparticles based upon treelike dendrimer structures made using porphyrin, cholic acid, amino acids, and polyethylene glycol.”
Civilian technology, Joel Mokyr notes, has also gone “small” — nanotechnology, genetic engineering, custom-engineered materials, “mass customization” through 3-D printing. If the Rouge plant looming over Dearborn was the iconic symbol of the industrial age, the iconic symbol of our information age is the smartphone in your pocket.
“Large” technology requires the standardization of masses of people, centralized command-and-control, conformity to social norms. Massive work forces and massive armies cannot operate optimally otherwise.
“Small” technology enables individuals to make personal choices, fashion their world to their own dimensions, deploy their own talents and pursue their interests in ways of their own choosing. Standardization yields to customization.
President Obama doesn’t seem to get this. He sees history as a story of progress from minimal government to ever-larger government. He’s only sorry that he hasn’t taken us farther on that track.
But history doesn’t proceed in a straight line; it moves around. “Large” technology made big government seem necessary in 1914. “Small” technology requires something different, something more adaptive today.
Indeed. You could almost write a book about that.
NANOTECHNOLOGY UPDATE: Proof of principle for nanoscale assembly line.
NANOTECHNOLOGY UPDATE: DARPA announces new program on nanoscale assembly and integration.
NANOTECHNOLOGY UPDATE: Seeing and touching a single synthetic molecular machine.
NANOTECHNOLOGY UPDATE: Nanotechnology-based next generation memory nears mass production.
NANOTECHNOLOGY UPDATE: Biotech lab in the cloud lowers entry barrier to nanotech research.
NANOTECHNOLOGY UPDATE: Debating the National Nanotechnology Initiative.
NANOTECHNOLOGY UPDATE: The atomically precise manufacture of quantum dots.
NANOTECHNOLOGY UPDATE: These Nanoparticles Could Clot Your Blood Faster—And Save Your Life.
NANOTECHNOLOGY UPDATE: Robust triangular RNA brick adds to RNA nanotechnology toolkit.
NANOTECHNOLOGY UPDATE: Photos from 2014 Foresight Technical Conference.
NANOTECHNOLOGY UPDATE: Novel properties for nanotechnology rebar-graphene reinforced with carbon nanotubes.
NANOTECHNOLOGY UPDATE: Novel properties for nanotechnology rebar-graphene reinforced with carbon nanotubes.
DNA NANOTECHNOLOGY replicates enzyme cascade. “In another advance along this pathway to atomically precise manufacturing, researchers have arranged two enzymes on a DNA scaffold to replicate the organization of an enzyme cascade inside a cell, passing a substrate molecule from one enzyme to the next.”
I LIKE THE IDEA, BUT I DOUBT IT’S PRACTICAL WITHOUT NANOTECHNOLOGY: Solar Roadways raises $1M for solar-panel covered roads.
NANOTECHNOLOGY UPDATE: Expanded DNA alphabet provides more options for nanotechnology.
WHILE WE WAIT FOR TRUE MOLECULAR MANUFACTURING, THE TRANSITIONAL NANOTECH CAN STILL BE HUGE: Nanotechnology to provide efficient, inexpensive water desalination.
NANOTECHNOLOGY UPDATE: Physicists suppress ‘stiction’ force that bedevils microscale machinery.
OBJECTIFIED BY SOCIETY’S ARTIFICIAL STANDARDS: Hollywood Actors: Six-Packs That Speak Lines.
Via Outside the Beltway, I see that Men’s Journal has a lengthy article on what it takes to be a male movie star these days. The short answer: 3 to 4 percent body fat, an incredibly carved six-pack and lovingly sculpted musculature. Because that combination does not normally occur in nature, the long answer involves nutritionists, traveling weight trainers, and more-than-occasional injections of testosterone and human growth hormone.
In other words, a Hollywood star is not so much an actor, or a body. It is a nearly starving body that has been stripped of almost all its naturally occurring subcutaneous fat, then artificially bolstered with various supplements and medical technology to make it look like a statue rather than a famine victim.
Nanotechnology will take care of that, eventually, at which point, not being difficult and rare, the look will go out of style. Meanwhile, I’m reminded of this article from back when Salon didn’t suck.
A SHORT REPORT FROM THE Foresight Institute’s 2014 Nanotechnology Conference.
WELL, THIS IS THE 21ST CENTURY, YOU KNOW: Wait, There’s Nanotechnology in My Food?
NANOTECHNOLOGY UPDATE: Nanomotors are controlled, for the first time, inside living cells.
NANOTECHNOLOGY UPDATE: Nanoparticle pinpoints blood-vessel plaques: A step toward identifying plaques vulnerable to rupture that causes heart attack and stroke. “By loading the surface with gadolinium ions instead of injecting them and letting them flow freely in the blood stream, the nanoparticle increases the relaxivity — or contrast from healthy tissue — by more than 10,000 times. That’s because the nanorod carries up to 2,000 molecules of the contrast agent, concentrating them at the plaque sites. Secondly, attaching the contrast agent to a nanoparticle scaffold reduces its molecular tumbling rates and leads to additional relaxivity benefit, the researchers explained. While the view is better, they are able to use 400 times less of the contrast agent because it’s delivered directly to plaques.”
NANOTECHNOLOGY UPDATE: RNA nanotechnology – fewer structures in living cells than in test tubes.
NANOTECHNOLOGY UPDATE: Nanoparticle That Mimics Red Blood Cell Shows Promise as Vaccine for Bacterial Infections.
FASTER PLEASE: World’s Smallest Pacemaker Can Be Implanted without Surgery.
Pacemaker surgery typically requires a doctor to make an incision above a patient’s heart, dig a cavity into which they can implant the heartbeat-regulating device, and then connect the pulse generator to wires delivered through a vein near the collarbone. Such surgery could soon be completely unnecessary. Instead, doctors could employ miniaturized wireless pacemakers that can be delivered into the heart through a major vein in the thigh.
On Monday, doctors in Austria implanted one such device into a patient—the first participant in a human trial of what device-manufacturer Medtronic says is the smallest pacemaker in the world. The device is 24 millimeters long and 0.75 cubic centimeters in volume—a tenth the size of a conventional pacemaker. Earlier this year, another device manufacturer, St. Jude Medical, bought a startup called Nanostim that makes another tiny pacemaker, and St. Jude is offering it to patients in Europe. This device is 41 millimeters long and one cubic centimeter in volume.
Doctors can implant such pacemakers into the heart through blood vessels, via an incision in the thigh. They use steerable, flexible tubes called catheters to push the pacemakers through a large vein.
It’s not nanotechnology, but it’s a great improvement.
NANOTECHNOLOGY UPDATE: Drug-carrying nanoparticles that can be taken orally in pill form.
NANOTECHNOLOGY UPDATE: Nanoparticle therapy for incurable brain cancer effective in mice.
IF YOU’RE INTERESTED IN NANOTECHNOLOGY, check out the 2014 Foresight Technical Conference, in Palo Alto this February.
INTERESTED IN NANOTECHNOLOGY? Check out the Foresight Institute’s 17th Annual Technical Conference on Nanotechnology, February 7-9, 2014, Crowne Plaza Cabana Hotel, Palo Alto.
NANOTECHNOLOGY UPDATE: Adding more chemical interactions to DNA nanotechnology.
NANOTECHNOLOGY UPDATE: Video: Eric Drexler On Transforming The Material Basis Of Civilization.
NANOTECHNOLOGY UPDATE: Nanotubes aren’t stiff if they aren’t straight. “Materials scientists have pursued the question of why vertically aligned carbon nanotube forests show much lower modulus values than expected. Now researchers from Georgia Tech have found that the nanotubes they fabricate contain kinks that dramatically diminish modulus value. In other words, the nanotubes are not straight; therefore, they are not stiff.”
NANOTECHNOLOGY UPDATE: Foresight Invitational Workshop: Nanotechnology for Developing Countries. Palo Alto, February.
NANOTECHNOLOGY UPDATE: New Treatment for Gonorrhea Prevents Reinfection: A nanoparticle-based cancer therapy has been found to thwart an antibiotic-resistant, sexually transmitted infection in mice. Given the growth of antibiotic resistant gonorrhea — and antibiotic resistance in general — this could be big.
NANOTECHNOLOGY UPDATE: Precise mechanical manipulation of individual long DNA molecules. “This advance is a very important nanotechnology that is especially important for DNA sequencing, and thus for personalized medicine, a major component of future medical technology.”
NANOTECHNOLOGY UPDATE: Video: Assembly and Manipulation of Molecules at the Atomic Scale.