I doubt it is really conscious arrogance. When you rely only on one mechanism to get access to truth, you start to forget that there are areas to which it does not apply. The idea that only scientifically determinable facts are truth throws out a lot more than God.
Science cannot make a definitive statement on whether God exists or what He is like. That is not within the realm where science is useful, namely mathematically describable or repeatable events based on consistent principles. Law is another area where science is not the primary method of determining the truth. We use courts because science cannot directly determine guilt or innocence of a crime. Forensic evidence is vital to the legal process, but the final decision is a matter of a judge and jury.
We owe our civilization’s success partly to the skillful application of scientific knowledge. Science has plenty of vexing problems to tackle like the protein folding problem and quantum gravity. What is the point of trying to disprove religion, when there are so many fascinating things for which science can be better used?
